Primary Regressive, But Metastasizing Melanoma!?
نویسندگان
چکیده
منابع مشابه
Metastasizing Melanoma Formation Caused by Expression
In human cutaneous malignant melanoma, a predominance of activated mutations in the N-ras gene has been documented. To obtain a mouse model most closely mimicking the human disease, a transgenic mouse line was generated by targeting expression of dominant-active human N-ras (N-Ras) to the melanocyte lineage by tyrosinase regulatory sequences (Tyr::N-Ras). Transgenic mice show hyperpigmented ski...
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ژورنال
عنوان ژورنال: Open Access Macedonian Journal of Medical Sciences
سال: 2019
ISSN: 1857-9655
DOI: 10.3889/oamjms.2019.048